DDU of Metered-Dose Inhalers
PRODUCT DESCRIPTION
MDI Metered Dose Inhaler Aerosol characteristics are relatively insensitive to changes in air flow rate because the Aerosolisation and dispersion mechanisms are dependent on the force generated by the propellant, rather than the patient’s inspiratory effort. Therefore, for MDI testing the flow rate is fixed at an arbitrary value of 28.3 L/min. A vacuum pump is used to draw air through the assembled test set-up at this flow rate. However, these test conditions are not applied for DDU Testing when the Metered Dose Inhaler is intended for use with an add-on device such as a spacer or valved holding chamber (VHC).
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BAC 100i – Breath Actuation Flow Controllers
The Breath Actuation Controller BAC 100i can also be used for the testing of Breath-Actuated (or Breath-Operated) MDIs. In this case, the BAC 100i is used to initiate the flow, simultaneously triggering the breath-actuated inhaler. |
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MDIs: Automated DDU Testing
Offering precisely controlled and repeatable delivery for Delivered Dose Uniformity (DDU) testing and Aerodynamic Particle Size Distribution (APSD) measurement, Vertus III automates all aspects of MDI, nasal spray and nasal aerosol dose sampling. Compatible with over 40 different collection device combinations including DUSA, Next Generation Impactor (NGI), Alberta Idealised Throat and Nasal Inlets, and Spray Force Tester, the Vertus III range offers total control over the test technique, but the flexibility to apply any industry-standard shake and fire test method. |
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